Question: Which Parent Does Klinefelter’S Syndrome Originate From?

Who is most likely to get Klinefelter’s syndrome?

Klinefelter syndrome occurs in about 1 out of 500 to 1,000 baby boys.

Women who get pregnant after age 35 are slightly more likely to have a boy with this syndrome than younger women..

What is the life expectancy of someone with Klinefelter syndrome?

How might Klinefelter syndrome affect your life? According to research, Klinefelter syndrome can shorten your life expectancy up to two years. However, you can still live a long, full life with this condition. The earlier you get treatment, the better your outlook will be.

What does XXY syndrome mean?

Klinefelter syndrome is a genetic condition in which a boy is born with an extra X chromosome. Instead of the typical XY chromosomes in men, they have XXY, so this condition is sometimes called XXY syndrome. Men with Klinefelter usually don’t know they have it until they run into problems trying to have a child.

How is Klinefelter’s inherited?

Klinefelter syndrome is not directly inherited – the additional X chromosome occurs as a result of either the mother’s egg or the father’s sperm having the extra X chromosome (an equal chance of this happening in either), so after conception the chromosome pattern is XXY rather than XY.

Can a girl have Klinefelter’s syndrome?

Klinefelter syndrome (47,XXY) results from an additional X chromosome on an XY background; therefore, this condition affects only males.

What are the chances of having a child with Klinefelter syndrome?

It is estimated that 1 in every 500 to 1,000 newborn males has an extra X chromosome, making Klinefelter syndrome one of the most common chromosomal disorders seen among newborns. Variants of Klinefelter syndrome (such as 48,XXXY, 49,XXXXY) are much rarer, occurring in 1 in 50,000 to 1 in 85,000 or fewer newborns.

Why are Klinefelter males tall?

From early school age, boys with Klinefelter’s syndrome tend to be taller (increased leg length) because testosterone normally stops boys growing after puberty. This increase in height is maintained throughout life. Patients with Klinefelter’s syndrome may have reduced coordination compared with other boys.

Who has Klinefelter syndrome?

Klinefelter syndrome affects about 1 in 650 newborn boys. It is among the most common sex chromosome disorders, which are conditions caused by changes in the number of sex chromosomes (the X chromosome and the Y chromosome).

Does Klinefelter syndrome run in families?

Klinefelter syndrome isn’t passed down through families like some genetic diseases. Instead, it happens randomly from an error in cell division when a parent’s reproductive cells are being formed. If one of these cells is part of a successful pregnancy, a baby boy will have the XXY condition.

Who first described Klinefelter syndrome?

In 1942, Dr. Harry Klinefelter and his coworkers first described the combination of features that has come to be recognized as Klinefelter Syndrome. By the late 1950’s, researchers discovered that men with this group of symptoms had an extra sex chromosome, XXY instead of the usual male arrangement of XY.

What does a person with Klinefelter syndrome look like?

Taller than average stature. Longer legs, shorter torso and broader hips compared with other boys. Absent, delayed or incomplete puberty. After puberty, less muscle and less facial and body hair compared with other teens.

What is XXY gender?

Klinefelter syndrome, also known as the XXY condition, is a term used to describe males who have an extra X chromosome in most of their cells. Instead of having the usual XY chromosome pattern that most males have, these men have an XXY pattern.

Is there a YY gender?

The Y chromosome contains a “male-determining gene,” the SRY gene, that causes testes to form in the embryo and results in development of external and internal male genitalia. If there is a mutation in the SRY gene, the embryo will develop female genitalia despite having XY chromosomes.

Which parent causes Klinefelter syndrome?

Klinefelter syndrome is not caused by anything the parents did or did not do. The disorder is a random error in cell division that happens when a parent’s reproductive cells are being formed.